Simultaneous transarterial chemoembolization and radiofrequency ablation for large hepatocellular carcinoma

更新时间:2023-05-28

【摘要】BACKGROUND Hepatocellular carcinoma(HCC) is a common cancer and a leading cause of tumor-related death.Patients with large HCC(≥ 8 cm) are at an advanced stage and have poor prognosis,and hepatic resection may not be suitable,and the incidence of postoperative recurrence is high.AIM To evaluate recurrence and mid-term survival of patients with large HCC treated by transcatheter arterial chemoembolization(TACE) and radiofrequency ablation(RFA).METHODS This was a retrospective study.From 2010 to 2013,46 consecutive patients with large HCC were treated with simultaneous TACE and RFA.Thirty-five of 46 patients had a single tumor.Progression-free survival(PFS) and overall survival(OS) were analyzed at 2 years and 3 years,respectively.RESULTS Forty-six patients treated by simultaneous TACE and RFA had no significant complications and treatment was successful.After 3 years,median PFS and OS were 10.21 ± 1.58 mo and 26.44 ± 2.26 mo,retrospectively.The survival rate was67.5% after 2 years and 55.67% after 3 years.CONCLUSION These preliminary data show that simultaneous TACE and RFA are safe and effective for large HCC.

【关键词】

阅读全文